肯尼斯 路易 克莱默博士

医学教育系主席

副教授

K克莱默

联系

KenKramer@xxskjgcjingtai.com
医学院
研究生院
神经科学(理学硕士)
医学(理学硕士)
医学教育
HLSB - Hixson Lied Science Building - 236

肯尼斯 路易 克莱默博士

医学教育系主席

副教授

肯尼斯·L·克莱默 是医学教育系的副教授和主席，也是M1组成部分的主任. 在接受Ph值后.D. from the University of Cincinnati in Anatomy and 细胞 Biology, 他在犹他大学做博士后工作，并在国家心脏中心做研究员, 肺, 血液研究所. His main area of research is in developmental glycobiology, 他与克雷顿的许多本科生和几个实验室合作，专注于斑马鱼的耳朵和大脑发育. Ken has a passion for medical education, seeking innovative approaches to teaching anatomy and histology. 除了多年活跃于美国解剖学家协会之外, 他喜欢通过奥马哈生物之眼和内布拉斯加州科学节向当地崭露头角的科学家提供外展项目.

研究的焦点

脊椎动物的内耳依靠感觉毛细胞顶端表面的特殊纤毛束来将声音和运动转化为电信号. 克莱默实验室利用早期斑马鱼胚胎的透明度来可视化纤毛与细胞外结构的联系如何调节内耳功能. 使用现代遗传和成像工具, 我们与校园内的几个实验室合作，以确定斑马鱼突变体和药物治疗如何影响听力和平衡行为.

简历

简历:肯尼斯 L. 克莱默博士

部门

医学教育

位置

副教授

出版物

  • 生物分子(巴塞尔，瑞士)
    面包师卡莉·E., CPT2 Deficiency Modeled in Zebrafish: Abnormal Neural Development, 电活动, 行为, and Schizophrenia-Related Gene Expression
    14:8, p. 914 2024
  • 神经科学前沿
    吉芬·金伯利P., 斑马鱼和小鼠内耳非感觉支持细胞中蛋白编码基因同源物的表达
    13 2019
  • 发展机制
    Thiessen Kevin D., Zebrafish otolith biomineralization requires polyketide synthase
    157, p. 1 - 9 2019
  • FASEB期刊
    Kcnq5a在斑马鱼内耳毛细胞中的作用
    33:S1 2019
  • FASEB期刊
    Thiessen Kevin，斑马鱼作为良性阵发性位置性眩晕的模型
    32:S1, p. 510.3 - 510.3 2018
  • 科学数据
    Barta Cody L., RNA-seq transcriptomic analysis of adult zebrafish inner ear hair cells
    5 2018
  • 发展动态
    Lundberg Yunxia Wang, Mechanisms of otoconia and otolith development
    244:3, p. 239 - 253 2015
  • 细胞的报道
    Venero Galanternik M., 硫酸肝素蛋白聚糖在细胞集体迁移过程中调节Fgf信号传导和细胞极性
    10:3, p. 414 - 428 2015
  • 血管生成
    Gorsi Bushra, 硫酸肝素编辑酶Sulf1在斑马鱼VegfA介导的动脉静脉身份中起着新的作用
    17:1, p. 77 - 91 2014
  • 《皇冠体育》
    嗨，史蒂芬·T., Yes-associated protein 65 (YAP)扩展神经祖细胞并调控pax3在神经板边界区的表达
    6:6 2011
  • Seminars in 细胞 and Developmental Biology
    克莱默·肯尼斯·L.在胚胎发育过程中观察到多面糖胺聚糖的特定方面
    21:6, p. 631 - 637 2010
  • 美国国家科学院院刊
    张甄, 大规模平行测序鉴定了Megf8基因与enu诱导的突变导致异位性
    106:9, p. 3219 - 3224 2009
  • 遗传学年度回顾
    克莱默·肯尼斯·L., Heparan Sulfate Core Proteins in 细胞-细胞 Signaling
    37, p. 461 - 484 2003
  • 细胞
    克莱默·肯尼斯·L.在爪蟾左右发育过程中，PKCγ调节syndecan-2内向外信号
    111:7, p. 981 - 990 2002
  • Cold Spring Harbor Symposia on Quantitative Biology
    克雷默K. L.心脏左右发展
    67, p. 37 - 43 2002
  • 细胞发育
    克莱默·肯尼斯·L., 外胚层syndecan-2作为细胞非自主的Vg1辅助因子介导迁移中胚层的左右轴形成
    2:1, p. 115 - 124 2002
  • 生物化学与生物物理文献
    克莱默·肯尼斯·L., 使用渗透泵的糖尿病大鼠胰岛素替代治疗使肝脏碳水化合物代谢关键酶的表达正常化
    368:2, p. 291 - 297 1999
  • 美国实验生物学学会联合会杂志
    克雷默K. L., 使用渗透泵的糖尿病大鼠胰岛素替代治疗使肝脏碳水化合物代谢关键酶的蛋白质和mrna水平正常化
    10:3, p. A461 1996

演讲

  • KD Thiessen, EM Supe和KL Kramer. (2019). Otol1a as a Biomarker for Vestibular Dysfunction in Zebrafish. Poster Presentation at Bellucci Symposium. 2019
  • KD Thiessen和KL Kramer. (2019). Balance and Biomarkers for Vestibular Disorders. 在奥马哈退伍军人管理局研究系列研讨会上的口头报告. 2019
  • CJ Altfillisch和KL Kramer. (2019). The Role of Stereocilin-B in Otolith Attachment. Poster Presentation at Midwest Student Biomedical Research Forum. 2019
  • KP Giffen, H Liu, KL Kramer, DZ He. (2019). Characterizing the Role of Kcnq5a in Zebrafish Inner Ear Hair 细胞s. Poster Presentation at Experimental Biology Annual Meeting. 2019
  • KD Thiessen, EM Supe和KL Kramer. (2019). Otol1a as a Biomarker for Vestibular Dysfunction in Zebrafish. Poster Presentation at Midwest Student Biomedical Research Forum. 2019
  • AJ布兰克和KL克莱默. (2019). Characterizing the Role of Kinociliin in the Zebrafish Inner Ear. Poster Presentation at Midwest Student Biomedical Research Forum. 2019
  • LL Bruce, E Dorchuck, BN Hassman, A Mezher, O Olucha, and KL Kramer. (2018). grp和grpr在斑马鱼线索恐惧记忆消失中的作用. Poster Presentation at Society for Neuroscience. 2018
  • N Choi, KL Kramer和Bruce LL. (2018). Role of gastrin-releasing peptide and its receptor in zebrafish behavior. HS-MACA学生年度生物医学研究会议口头报告. 2018
  • KD Thiessen, EM Supe和KL Kramer. Zebrafish Otolith Biomineralization Requires Polyketide Synthase. (2018). Poster presentation at International Zebrafish Society Conference. 2018
  • KD Thiessen, EM Supe和KL Kramer. (2018). Otolin-1a作为斑马鱼微重力暴露后前庭功能障碍的生物标志物. Poster presentation at COBRE External Advisory Committee Meeting. 2018
  • KD Thiessen, EM Supe和KL Kramer. Zebrafish as a Model for Benign Paroxysmal 位置al Vertigo. (2018). Poster Presentation at Experimental Biology Annual Meeting. 2018
  • KD Thiessen, EM Supe和KL Kramer. (2018). Otolin-1a作为斑马鱼微重力暴露后前庭功能障碍的生物标志物. Oral presentation at Nebraska Academy of 科学 Annual Meeting. 2018
  • E Supe, KD Thiessen和KL Kramer. (2018). Zebrafish as a Model for Benign Paroxysmal 位置al Vertigo. Poster Presentation at Creighton's St 阿尔贝二世亲王的一天. 2018
  • B Hassman, E Dorchuck, C Prince, K Reidelberger, KL Kramer, and LL Bruce. (2018). Comparison of behavioral tests to assess fear and anxiety in a teleost, 鲐鱼类, 还有一只两栖动物, 非洲爪蟾蜍tropicalis. Poster Presentation at Creighton's St 阿尔贝二世亲王的一天. 2018
  • 斑马鱼作为表征前庭功能障碍生物标志物的模型. Seminar at Boys Town National Research Hospital. 2018
  • A Mezher, LL Bruce, KL Kramer. (2018). Evolution of Genetic Networks Regulating Fear 行为s. Poster at Midwest Student Biomedical Research Forum. 2018
  • ST Stringham, KP Giffen, H Liu, KL Kramer, DZ He. (2018). 谷氨酸转运蛋白slc1A3同源物在斑马鱼和小鼠内耳毛细胞中的富集. Poster at Midwest Student Biomedical Research Forum. 2018
  • KP Giffen, H Liu, L Chen, ST Stringham, KL Kramer, KW Beisel, and DZ He. (2018). 斑马鱼和小鼠内耳非感觉支持细胞群中基因同源物的独特表达. Poster at Midwest Student Biomedical Research Forum. 2018
  • KP Giffen, H Liu, L Chen, ST Stringham, KL Kramer, KW Beisel, and DZ He. (2018). 斑马鱼和小鼠内耳非感觉支持细胞群中基因同源物的独特表达. 在耳鼻喉科研究协会年会上的海报展示. 2018
  • H Liu, L Chen, KP Giffen, Y Li, KL Kramer, KW Beisel, and DZ He. (2018). 斑马鱼和小鼠毛细胞特化差异的分子机制. 在耳鼻喉科研究协会年会上的海报展示. 2018
  • B Hassman, E Dorchuck, C Prince, K Reidelberger, KL Kramer, and LL Bruce. (2017). Comparison of behavioral tests to assess fear and anxiety in a teleost, 鲐鱼类, 还有一只两栖动物, 非洲爪蟾蜍tropicalis. Poster Presentation at Society for Neuroscience. 2017
  • CJ Altfillisch, DB Nerland, CJ Inserra, MF Chlopek, and KL Kramer. (2017). Stereocilin-b将斑马鱼的耳石连接到内耳的感觉毛细胞. Poster at Experimental Biology Annual Meeting. 2017
  • KD Thiessen, LN Higuchi和KL Kramer. Polyketide Synthase is Required for Zebrafish Otolith Biomineralization. (2017). Poster Presentation at Experimental Biology Annual Meeting. 2017
  • B Hassman, E Dorchuck, KL Kramer, and LL Bruce. (2017). 行为al Tests for Assessing Learning in Xenopus Tropicalis. Oral Presentation at The Nebraska Academy of 科学 Annual Meeting. 2017
  • CL哈里森和KL克莱默. Characterization of Specific Glycans in the Zebrafish Inner Ear. (2017). Poster Presentation at Creighton Honors Day. 2017
  • SH Byer, LL Bruce和KL Kramer. 了解杏仁核蛋白聚糖-3在斑马鱼厌恶行为反应中的作用. (2017). Poster Presentation at Creighton Honors Day. 2017
  • CJ Altfillisch, DB Nerland, CJ Inserra, MF Chlopek, and KL Kramer. (2017). Stereocilin-b将斑马鱼的耳石连接到内耳的感觉毛细胞. Poster Presentation at Creighton's St 阿尔贝二世亲王的一天. 2017
  • E Supe, KD Thiessen和KL Kramer. (2017). Zebrafish as a Model for Benign Paroxysmal 位置al Vertigo. Poster Presentation at Creighton's St 阿尔贝二世亲王的一天. 2017
  • HJ Lang和KL Kramer. (2017). Investigation of Enhancers that Drive Specific Expression in the Amygdala. Poster Presentation at Creighton's St 阿尔贝二世亲王的一天. 2017
  • CL哈里森和KL克莱默. (2017). Characterization of Specific Glycans in the Zebrafish Inner Ear. Poster Presentation at Creighton's St 阿尔贝二世亲王的一天. 2017
  • KD Thiessen, LN Higuchi和KL Kramer. (2017). Polyketide Synthase is Required for Zebrafish Otolith Biomineralization. Poster Presentation at Midwest Student Biomedical Research Forum. 2017
  • JE Marvin和KL Kramer. (2017). 糖基转移酶Loki使用高能供体间接转糖基化甲基伞形酮. Poster at Midwest Student Biomedical Research Forum. 2017
  • JH Werner, KL Kramer和LL Bruce. (2017). 鸡脑内基因特异性杏仁核神经元同源物的定位, 家蝇. Poster at Midwest Student Biomedical Research Forum. 2017
  • CJ英瑟拉和KL克莱默. 立体声蛋白在斑马鱼内耳发育中有独特的作用. 在耳鼻喉科研究协会年会上的海报展示. 2017
  • B蒂姆，KL克莱默，和LL布鲁斯. (2016). 鸡胚脑基因特异性杏仁核区域的同源定位. HS-MACA学生年度生物医学研究会议海报展示. 2016
  • "Sugar Balance: How Glycans Control Inner Ear Development" 2016
  • Catharine N Kral, Benjamin F Kopecky, and 肯尼斯·L·克莱默. TECTA, Otog, and Otogl Influence Zebrafish Otolith Organization. Poster Presentation at Creighton Honor's Day. 2016
  • Catharine N Kral, Benjamin F Kopecky, and 肯尼斯·L·克莱默. TECTA, Otog, and Otogl Influence Zebrafish Otolith Organization. 海报简介会. 阿尔贝二世亲王的一天. 2016
  • 凯文·D·蒂森和肯尼斯·L·克莱默. Role of Otolin-1b During Otolith Nucleation in Zebrafish. 圣堂口头报告. 阿尔贝二世亲王的一天. 2016
  • KD Thiessen和KL Kramer. The Otolithic Membrane Mediates Otolith Organization. Poster Presentation at Experimental Biology Annual Meeting 2016
  • C Barta, H Liu, KL Kramer, KW Beisel, DZ He. (2016). Transcriptome Characterization of Adult Zebrafish Inner-Ear Hair 细胞s. 在耳鼻喉科研究协会年会上的海报展示. 2016
  • 维兰纽瓦和克莱默. Age-Related Changes in the Inner Ear of the Adult Zebrafish. Poster Presentation at Creighton Honor's Day. 2015
  • C Altfillisch, K Arnold, L Higuchi, KL Kramer, MG Nichols, HC Jensen Smith. 再生和非再生感觉细胞氨基糖苷进入和线粒体代谢的差异. 海报简介会. 阿尔贝二世亲王的一天. 2015
  • K Arnold, C Altfillisch, L Higuchi, KL Kramer, MG Nichols, HC Jensen Smith. 再生和非再生感觉细胞线粒体代谢的差异. 海报简介会. 阿尔贝二世亲王的一天. 2015
  • KD Thiessen和KL Kramer. 在斑马鱼早期耳发育过程中，内淋巴促进耳石成核. 海报简介会. 阿尔贝二世亲王的一天. 2015
  • CJ英瑟拉和KL克莱默. Visualization of Stereocilin in the developing zebrafish ear. Poster Presentation at Midwest Student Biomedical Research Forum. 2015
  • KD Thiessen和KL Kramer. 在斑马鱼早期耳发育过程中，内淋巴促进耳石成核. Poster Presentation at Midwest Student Biomedical Research Forum. 2015
  • Otolith organization is mediated by otogelin-like. 在耳鼻喉科研究协会年会上的口头报告. 2015
  • "Otogelin in Zebrafish Otolith Attachment and Organization" 2014
  • 斑马鱼种子耳石:甜 & salty mediators of zebrafish ear development 2014
  • "From Sweet to salty: mediators of zebrafish ear development" 2013
  • 斑马鱼的听觉发育. 2013
  • Keratan sulfate mediates zebrafish ear development. 2013

状态

  • Role of Glycosaminoglycans in Zebrafish Development

  • Direct analysis of glycans during zebrafish development

联邦

  • Role of Keratan Sulfate in Zebrafish Ear Development

其他

  • Role of Kinocilia-Specific Proteins in Zebrafish Vestibular Function.

  • gpc3在恐惧行为中的作用. 学院研究基金.

  • ZOIC-Zebrafish in Omaha Inner City Classrooms

奖

  • 金苹果
    CUSOM Class of 2025 and the Class of 2024
  • 明日教学教师奖
    皇冠体育博彩大学学生会
  • 金苹果奖
    Class of 2022, 皇冠体育博彩大学 医学院
  • 专业教学奖
    皇冠体育博彩大学 医学院
  • 课程/见习主任奖
    皇冠体育博彩大学 医学院
  • 基础科学教学学者奖
    皇冠体育博彩大学 医学院